What is Mesotherapy?

Mesotherapy is the latest rage for lipo-sculpting away fat accumulations that exercise doesn't seem to reduce. Pioneered in France by Dr. Michel Pistor in 1952,  mesotherapy is a non-surgical, relatively painless injection technique that has many applications.  Mesotherapy promotes natural ways to enhance circulation, lymphatic drainage, and fat-burning by reversing abnormal physiology.

Applications practiced at Kokopelli Health & Wellness replace the need for liposuction with injections that melt away fat by changing the function of Adipocyte Cell Membrane (ACM), decreasing Insulin Resistance (IR), and changing genetic expression of the "Thrifty Gene" - leading to reduction of fat storage and enhancing fat burning in the fat storage- Adipose cells.

The Procedure

Mesotherapy involves customized injections of Phosphatidyl Choline (PPC), vitamins, herbs, amino acids or medications just under the skin in the mesoderm (hence the name Mesotherapy).  The results are dramatic.  After completing a series of treatments, generally over a 3 month period,  patients can see marked improvements in the skin - less dimpling and the shedding of approximately 10 pounds of fat and reduction in 1 to 2 clothing sizes.

The injections are safe and virtually painless.  In comparison to surgery, there is no post-operative down time, no heavy bandages or girdles, and no general anesthesia risks.  Multiple injections are made into the problem areas of fat and cellulite, millimeters under the skin.  Local anesthetics are used to diminish any discomfort of the injections.  Pain gels or numbing creams are used after the procedure to lessen any discomfort post procedure.  For those with lower pain thresholds, prescription pain medications may be prescribed.  The procedure generally takes 20-30 minutes to complete.

Generally, 8 to 10 treatments are required, but thin problem with problem areas such as "saddlebags" or "love handles", those areas refractory to diet and exercise, may require fewer treatments.  Few side effects are normally seen with mesotherapy, but can include bruising, local swelling, and tenderness at the injection sites.  These generally resolve in 1 to 2 weeks.

How Mesotherapy Works

Excessive Adipose tissue (fat cells) increase Insulin Resistance (IR) and Fasting Blood Insulin levels, which cause accumulation of a phospholipid - spingomyelin (SM) and a decrease in Phosphatidyl Choline (PPC) in the cell membranes.  This decreases the fluidity of the membrane and the transport of hormones, cell messenger molecules (cytokines), and other needed cellular material (ligands).  This imbalance between SM and PPC lead to diminished genetic expression of "Thrifty Gene" Adipocyte (fat cell) Nuclear Receptors.  The effect is that the "master nuclear controller" Peroxisome proliferator-activated receptor-gamma (PPAR-G) has different function and metabolism of lipids (fats).  This is the major determinant of waist circumference or increased fat deposition (Diabetes, 2003 July: 52(7):1673-6).

What this means is that the science of how mesotherapy works has been firmly established.  By replenishing the PPC in the Adipose Cell membrane (ACM), the cell membrane fluidity returns to normal resulting in localized fat lipolysis (burning).  Since this decrease in PPC in the cellular membranes is universal (50% decreasing to 10% by age 80), resulting in the loss of cellular energy, it may be the most dramatic single event in aging and fat metabolism.

The other components of the mesotherapy injections - vitamins, amino acids, herbs, or medications, can enhance the fat burning effect.  By enhancing circulation, lymph drainage and/or cellular metabolism, the cell's physiology (function) is improved, as well as removing toxins and by-products of metabolism.

Summary of Mesotherapy

Mesotherapy injections of Phosphatidyl Choline, the major phospholipid in our cell membranes, and other vitamins, herbs, amino acids, or medications - enhance the fat burning in the cells for localized weight reduction and improvements in the appearance of cellulite.  To set up a consultation, call Tonya at (970) 263-4660.